Causes
We don’t fully understand the causes of type 1 diabetes, but we do know there are a few factors at play.
What we know
Type 1 diabetes (T1D) is an autoimmune condition where the pancreas stops producing insulin due to the immune system attacking the beta cells, which produce insulin. Research is ongoing to identify what causes type 1 diabetes—and how to stop it. Here’s what we know about onset.
Genes and family history
Certain genes increase the likelihood of an individual developing T1D, as can a family history of the condition. If you have an immediate family member with T1D, your chances of developing the condition are 1 in 20, which is 15 times higher than the general population.
Environmental triggers
Environmental factors, including viruses, are another factor behind T1D onset. Some researchers believe that certain viruses may specifically target beta cells, and as the body’s immune response tries to combat these viruses, it may mistakenly attack and damage the beta cells.
Immune response
Once T1D is triggered, the body starts attacking the beta cells, which produce insulin. This attack can be detected through biochemical signs called autoantibodies, which appear well before any symptoms of type 1 diabetes are observed. As the immune system continues to attack and destroy more beta cells, insulin production decreases, leading to abnormal blood-sugar levels. Eventually, the number of destroyed beta cells becomes so high, and insulin production drops so low that symptoms of type 1 diabetes start to appear.
T1D cannot be prevented through diet or exercise
It is important to understand that T1D is not caused by diet. However, certain dietary factors might be involved in the development of type 2 diabetes.
Similarly, the risk of a type 1 diabetes diagnosis is not influenced by factors such as lifestyle, activity level, socioeconomic status, or habits.
Learn more T1D basics
Recognize the early warning signs of T1D
Therapies for treating type 1 diabetes
Get the facts about living with T1D
